Dydrogesterone Paten. Dydrogesterone has been marketed for conditions related to progesterone insufficiency for more than 50 years The safety and tolerability profile of the drug has been established with an estimated exposure to 113 million patients globally 8 The use of dydrogesterone is specific to the regulatory approval in each country and includes the treatment of threatened or recurrent.

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Dydrogesterone is used on its own or together with other medicines to treat conditions caused by progesterone deficiency such as menstrual disorders infertility threatened or habitual abortion and endometriosis (a problem caused by growth of the womb lining outside the womb) This medicine may be used to treat other conditions as decided by.

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20150402 Priority to PCT/CN2015/000231 priority Critical patent/WO2016154772A1/zh 20161006 Publication of WO2016154772A1 publication Critical patent/WO2016154772A1/zh Links Espacenet Global Dossier PatentScope Discuss 150000001875 compounds Chemical class 0000 claims abstract description 58 238000002360 preparation methods Methods 0000.

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Dydrogesterone is a progestin or a synthetic progestogen and hence is an agonist of the progesterone receptor the biological target of progestogens like progesterone The medication is an atypical progestogen and does not inhibit ovulation It has weak antimineralocorticoid activity and no other important hormonal activity.

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Description Dydrogesterone is a progestogen which has structures related to progesterone It produces a complete secretory endometrium in a uterus primed by oestrogen providing protection against increased risk of endometrium hyperplasia and/or carcinogenesis Dydrogesterone lacks oestrogenic anabolic androgenic thermogenic and corticoid.